Comparison of CPAP and oxygen therapy for treatment of postoperative hypoxaemia in dogs. J Small Anim Pract. doi: 10.1111/jsap.13295.

García-Sanz V, Canfrán S, Gómez de Segura IA, Aguado D. Effect of recumbency and body condition score on open-lung positive end-expiratory pressure and respiratory system compliance following a stepwise lung recruitment manoeuvre in healthy dogs during general anaesthesia. Res Vet Sci 2020;132:177-185. doi: 10.1016/j.rvsc.2020.06.016.

Arenillas M, Aguado D, Canfrán S, Sánchez-López A, Gómez de Segura IA. Sedative effects of two doses of alfaxalone in combination with methadone and a low dose of dexmedetomidine in healthy Beagles. Vet Anaesth Analg. 2020;47(4):463-471. doi: 10.1016/j.vaa.2019.12.010.

Bustamante R, Gómez de Segura IA, Canfrán S, Aguado D. Effects of ketamine or midazolam continuous rate infusions on alfaxalone total intravenous anaesthesia requirements and recovery quality in healthy dogs: a randomized clinical trial. Vet Anaesth Analg. 2020;47(4):437-446. doi:10.1016/j.vaa.2019.10.010.

González-Blanco P, Canfrán S, Mota R, Gómez de Segura IA, Aguado D. Effects of a single paracetamol injection on the sevoflurane minimum alveolar concentration in dogs. Can J Vet Res. 2020;84(1):37-43.

Aguado D, Bustamante R, García-Sanz V, González-Blanco P, Gómez de Segura IA. Efficacy of the Parasympathetic Tone Activity monitor to assess nociception in healthy dogs anaesthetized with propofol and sevoflurane. Vet Anaesth Analg 2020; 47(1):103-110 Doi: 10.1016/j.vaa.2019.05.014.

García-Sanz V, Aguado D, Gómez de Segura IA, Canfrán S. Comparative effects of open-lung positive end-expiratory pressure (PEEP) and fixed PEEP on respiratory system compliance in the isoflurane anaesthetised healthy dog. Res Vet Sci 2019;127:91-98. Doi: 10.1016/j.rvsc.2019.10.016

Arenillas M, Caro-Vadillo A, Gómez de Segura IA. Anesthetic management of a dog with severe subaortic stenosis and mitral valve disease complicated with atrial fibrillation undergoing ovariohysterectomy. Open Vet J. 2019;9(2):157-163. Doi: 10.4314/ovj.v9i2.11

Sasaki K, Shiga T, Gómez de Segura IÁ. Advantages of a Novel Device for Arterial Catheter Securement in Anesthetized Dogs: A Pilot Randomized Clinical Trial. Front Vet Sci. 2019;6:171. Doi: 10.3389/fvets.2019.00171. Vieitez V, Ezquerra LJ, López Rámis V, Santella M, Gómez de Segura IA. Retrograde intubation in a dog with severe temporomandibular joint ankylosis: case report. BMC Veterinary Research 2018; 14:118. Doi: 10.1186/s12917-018-1439-7.

Bustamante R, Daza MA, Canfrán S, García P., Suárez M, Trobo I, Gómez de Segura, IA. Comparison of the postoperative analgesic effects of cimicoxib, buprenorphine and their combination in healthy dogs undergoing ovariohysterectomy. Vet Anaesth Analg 2018;45(4):545-556. Doi: 10.1016/j.vaa.2018.01.003.

Arenillas M, Gomez de Segura IA. Anaesthetic effects of alfaxalone administered intraperitoneally alone or combined with dexmedetomidine and fentanyl in the rat. Lab Anim. 2018: 52(6):588-598. Doi: 10.1177/002367721-8764214.

Aguado D, Bustamante R, Gómez de Segura IA. Toll-like receptor 4 deficient mice do not develop remifentanil-induced mechanical hyperalgesia: An experimental randomised animal study. Eur J Anaesthesiol. 2018;35(7):505-510. Doi: 10.1097/EJA.0000000000000803.

Bustamante R, Aguado D, Cediel R, Gómez de Segura IA, Canfrán S. Clinical comparison of the effects of isoflurane or propofol anaesthesia on mean arterial blood pressure and ventilation in dogs undergoing orthopaedic surgery receiving epidural anaesthesia. Vet J 2018;233:49-54. Doi: 10.1016/j.tvjl.2018.01.002.

Sasaki, K., Mutoh, T., Shiga, T., Gómez de Segura, IA. (2018) Successful intensive management in dogs with postoperative cutaneous drug hypersensitivity Veterinary Record Case Reports 2018;6: e000613. doi: 10.1136/vetreccr-2018-000613.

Complicaciones anestésicas frecuentes en gatos y su prevención. Anestesia y analgesia felina. Coordinador Monografía Canis et Felis 2018;151(2,abril):52-58. ISSN1133-2751

Vieitez V, Álvarez Gómez de Segura I, López Rámis V, Santella M, Ezquerra LJ. Total intravenous anaesthesia in a goat undergoing craniectomy. BMC Vet Res. 2017;13(1):287. doi: 10.1186/s12917-017-1205-2.

Sasaki, K., Mutoh, T., Shiga, T., Gómez de Segura, IA. Unsuccessful resuscitation with epinephrine in a dog with suspected severe perioperative anaphylaxis Veterinary Record Case Reports 2017;5: e000440. doi: 10.1136/vetreccr-2017-000440

Vieitez V, Gómez de Segura IÁ, Martin-Cuervo M, Gracia LA, Ezquerra LJ. Successful use of lipid emulsion to resuscitate a foal after intravenous lidocaine induced cardiovascular collapse. Equine Vet J 2017;49(6):767-769017. Doi: 10.1111/evj.12699.

Costa-Farré C, Climent F, Moreira da Fonseca C, Gómez de Segura IA.. Nonfatal infusion pump-related venous air embolism in a dog. J Am Vet Med Assoc. 2017;251(3):291-294. Doi: 10.2460/javma.251.3.291.

Pons A, Canfrán S, Benito J, Cediel-Algovia R, Gómez de Segura IA. Effects of dexmedetomidine administered at acupuncture point GV20 compared to intramuscular route in dogs. J Small Anim Pract. 2017 Jan;58(1):23-28. doi: 10.1111/jsap.12601.

Ruiz-Pérez D, Benito J, Largo C, Polo G, Canfrán S, Gómez de Segura IA. Metamizole (dipyrone) effects on sevoflurane requirements and postoperative hyperalgesia in rats. Lab Anim. 2017;51(4):365-375 doi:10.1177/0023677216-671553.

Re M, Blanco-Murcia J, Villaescusa A, De Gaspar I, de Segura IA. Comparison of paravertebral blockade techniques with and without ultrasound guidance in calves. Am J Vet Res. 2016;77(11):1187-1193. DOI: 10.2460/ajvr.77.11.1187.

Canfrán S, Bustamante R, González P, Cediel R, Re M, de Segura IA. Comparison of sedation scores and propofol induction doses in dogs after intramuscular administration of dexmedetomidine alone or in combination with methadone, midazolam, or methadone plus midazolam. Vet J. 2016;210:56-60. doi: 10.1016/j.tvjl.2016.01.015.

Figueiró MR, Soares JH, Ascoli FO, Werre S, Gómez de Segura IÁ. Isoflurane MAC determination in dogs using three intensities of constant-current electrical stimulation. Vet Anaesth Analg. 2016;43(5):464-71. doi: 10.1111/vaa.12341.

Re M, Canfrán S, Largo C, Gómez de Segura IA. Effect of Lidocaine–Ketamine Infusions combined with Morphine or Fentanyl in Sevoflurane-Anesthetized Pigs. J Am Assoc Lab Anim Sci 2016;55(3):317-30.

Re M, Blanco J, Gómez de Segura IA. Ultrasound-Guided Nerve Block Anesthesia. Vet Clin North Am Food Anim 2016;32(1):133-147 dx.doi.org/10.1016/ j.cvfa.2015.09.003.

Ruiz-Pérez D, Benito J, Polo G, Largo C, Aguado D, Sanz L, Gómez de Segura IA. The Effects of the Toll-Like Receptor 4 Antagonist, Ibudilast, on Sevoflurane's Minimum Alveolar Concentration and the Delayed Remifentanil-Induced Increase in the Minimum Alveolar Concentration in Rats. Anesth Analg. 2016;122(5):1370-6. doi: 10.1213/ANE.0000000000001171.

Abreu M, Aguado D, Benito J, Garcia-Fernandez J, Gomez de Segura IA. Tramadol-induced hyperalgesia and its prevention by ketamine in rats: A randomised experimental study. Eur J Anaesthesiol 2015;32(10):735-741; doi: 10.1097/EJA. 0000000000000296.

Canfrán S, Cediel R, Sández I, Caro-Vadillo A, Gómez de Segura IA. Evaluation of an oesophageal Doppler device for monitoring cardiac output in anaesthetised healthy normotensive dogs. J Small Anim Pract 2015; 56(7): 450-455; doi: 10.1111/jsap.12362.

Puighibet Z, Costa-Farré C, Santos L, Canfrán S, Gómez de Segura IA. The sedative effects of intramuscular low dose medetomidine in combination with butorphanol or methadone in dogs. Vet Anaesth Analg 2015;42:590–596; doi: 10.1111/vaa.1225.

Abreu M, Aguado D, Benito J, Garcia-Fernandez J, Gomez de Segura IA. Hyperalgesia and increased sevoflurane Minimum Alveolar Concentration induced by opioids in the rat. Eur J Anaesthesiol 2015;32(4):232-41. doi: 10.1097/EJA. 0000000000000188.

Aguado D, Abreu M, Benito J, Garcia-Fernandez J, Gomez de Segura IA. Amitriptyline, minocycline and maropitant reduce the sevoflurane minimum alveolar concentration and potentiate remifentanil but do not prevent acute opioid tolerance and hyperalgesia in the rat. Eur J Anaesthesiol 2015; 32(4):248-54. doi: 10.1097/ EJA.0000000000000098.

Villalba M, Santiago I, Gomez de Segura IA. Effects of a constant rate infusion of medetomidine-propofol on the isoflurane minimum alveolar concentrations in horses. Vet J 2014;202(2):329-33. doi:10.1016/j.tvjl.2014.08.007

Giral M, García-Olmo DC, Gómez-Juárez M, Gómez de Segura IA. Anaesthetic effects in the ferret of alfaxalone alone and in combination with medetomidine or tramadol: a pilot study. Lab Anim 2014;48:313-20. doi: 10.1177/ 0023677214539­1­50

Re R, Blanco-Murcia FJ, Villaescusa Fernández A, De Gaspar Simón I, Gómez de Segura IA. Ultrasound-guided anaesthetic blockade of the pelvic limb in calves, Vet J 2014;200(3):434-439. doi:10.1016/j.tvjl.2014.04.010.

Villaverde-Morcillo S, Benito Garcıa-Sanchez R, Martin-Jurado O, Gomez de Segura IA. Comparison of isoflurane and alfaxalone (alfaxan) for the induction of anesthesia in flamingos (phoenicopterus roseus) undergoing orthopedic surgery. J Zoo Wildl Med 2014;45(2):362–367.

Re M, Blanco-Murcia FJ, San Miguel JM, Gómez de Segura IA. Reversible chemical restraint of free-range cattle with a concentrated combination of tiletamine-zolazepam, ketamine, and detomidine. Can J Vet Res. 2013 Oct;77(4):288-92.

Canfran S, Gomez de Segura IA, Cediel R, Garcia-Fernandez J. Effects of fluid load on cardiovascular function during stepwise lung recruitment manoeuvre in healthy dogs. Vet J 2013;197(3):800-805. doi: 10.1016/j.tvjl.2013.05.013

Garcia-Fernandez J, Canfran S, Gomez de Segura IA Suarez-Sipmann F, Aguado D, Hedenstierna G. Pressure safety range of barotrauma with lung recruitment manoeuvres: a randomized experimental study in a healthy animal model. Eur J Anesthesiol 2013;30(9):567-574. doi: 10.1097/EJA.0b013e3283607875

Aguado D, Benito J, Abreu M, Garcia-Fernandez J, Gomez de Segura IA. Effects of naloxone on opioid-induced hyperalgesia and tolerance to remifentanil under sevoflurane anesthesia in rats. Anesthesiology 2013;118(5):1160–9. DOI: 10.1097/ALN.0b013e31828875 26

2012   Granados MM, Domínguez JM, Fernández-Sarmiento A, Funes FJ, Morgaz J, Navarrete R, Carrillo JM, Rubio M, Muñoz-Rascón P, Gómez de Segura IA, Gómez-Villamandos R. Anaesthetic and cardiorespiratory effects of a constant-rate infusion of alfaxalone in desflurane-anaesthetised sheep. Vet Rec 2012;171(5):125. doi: 10.1136/vr.100487.

Abreu M, Aguado D, Benito J, de Segura IA. Reduction of the sevoflurane minimum alveolar concentration induced by methadone, tramadol, butorphanol and morphine in rats. Lab Anim 2012; 46: 200–206 DOI:10.1258/la.2012.010066

Canfran S, Gómez de Segura IA, Cediel R, García-Fernández J, Effects of a stepwise lung recruitment manoeuvre on lung compliance and arterial blood oxygenation in healthy dogs. Vet J 2012;194(1):89-93. DOI: 10.1016/j.tvjl.2012.02.021

López-Sanromán J, Holmbak-Petersen R, Santiago I, Gómez de Segura IA, Barrey E. Gait anal-ysis using 3D accelerometry in horses sedated with xylazine. Vet J. 2012;193:212-216. DOI: 10.1016/j.tvjl.2011.10.012

Aguado D, Abreu M, Benito J, García-Fernández J, Gómez de Segura IA. The effects of gabapentin on acute opioid tolerance to remifentanil under sevoflurane anesthesia in rats. Anesth Analg. 2012;115(1):40-45. DOI: 10.1213/ANE.0b013e31825427­ 27)

Villalba M, Santiago I, Gomez de Segura IA. Effects of constant rate infusion of lidocaine and ketamine, with or without morphine, on isoflurane MAC in horses. Eq Vet J 2011;43(6):721-726. DOI: 10.1111/j.2042-3306.2010.00355.x

Aguado D, Abreu M, Benito J, García-Fernández J, Gómez de Segura IA. Ketamine and remifentanil interactions on the sevoflurane minimum alveolar concentration and acute opioid tolerance in the rat. Anesth Analg. 2011;113(3):505-12. DOI: 10.1213/ANE.0b013e318227517a

Aguado D, Benito J, Gómez de Segura IA. Reduction of the minimum alveolar concentration of isoflurane in dogs using a constant rate of infusion of lidocaine-ketamine in combination with either morphine or fentanyl. Vet J. 2011;189(1):63-66. DOI:10.1016/j.tvjl.2010.05. 029

Re M, Blanco J, Gómez de Segura IA. Chemical restraint and anaesthetic effects of a tiletam-ine-zolazepam/ketamine/detomidine combination in cattle. Vet J 2011;190:66–70 DOI:10.1016/ j.tvjl.2010.09.023