Grupos de investigación

Publicaciones recientes del grupo de investigación

Últimas publicaciones

  • Macho-González A, Ticona LA, Redondo-Castillejo R, Hernández-Martín M, Sánchez-Muniz FJ, Hernáiz MJ, Bastida S, Benedí J, Bocanegra A, López-Oliva ME, Mateos-Vega C, Garcimartín A (2024). The preventive and therapeutic consumption of meat enriched with carob fruit extract, rich in phenolic compounds, improves colonic antioxidant status in late-stage T2DM rats. Food Chem. 450:139339. doi: 10.1016/j.foodchem.2024.139339
  • Hernández-Martín M, Macho-González A, Garcimartín A, López-Oliva ME, Bocanegra A, Redondo-Castillejo R, Bastida S, Benedí J, Sánchez-Muniz FJ (2024). Silicon-enriched meat positively improves plasma lipidaemia and lipoproteinaemia, LDLr, and insulin capability and the signalling pathway induced by an atherogenic diet in late-stage type 2 diabetes mellitus rats. Food & Function. 15(3):1513-1526. doi: 10.1039/d3fo04103d.
  • Cofrades S, Gómez-Estaca J, Álvarez MD, Garcimartín A, Macho-González A, Benedí J, Pintado T (2023). Influence of the Oil Structuring System on Lipid Hydrolysis and Bioaccessibility of Healthy Fatty Acids and Curcumin. Gels. 10(1):33. doi: 10.3390/gels10010033.
  • Redondo-Castillejo R, Garcimartín A, Hernández-Martín M, López-Oliva ME, Bocanegra A, Macho-González A, Bastida S, Benedí J, Sánchez-Muniz FJ (2023). Proanthocyanidins: Impact on Gut Microbiota and Intestinal Action Mechanisms in the Prevention and Treatment of Metabolic Syndrome. International Journal of Molecular Sciences. 24(6):5369. doi: 10.3390/ijms24065369.
  • Cofrades S, Garcimartín A, Pérez-Mateos M, Saiz A, Redondo-Castillejo R, Bocanegra A, Benedí J, Dolores Álvarez M (2023). Stabilized soy protein emulsion enriched with silicon and containing or not methylcellulose as novel technological alternatives to reduce animal fat digestion. Food Res Int. 170:112833. doi: 10.1016/j.foodres.2023.112833.
  • Hernández-Martín M, Bocanegra A, Redondo-Castillejo R, Macho-González A, Sánchez-Muniz FJ, Benedí J, Bastida S, García-Fernández RA, Garcimartín A, López-Oliva ME (2022). Could Duodenal Molecular Mechanisms be Involved in the Hypocholesterolemic Effect of Silicon Used as Functional Ingredient in Late-Stage Type 2 Diabetes Mellitus? Molecular Nutrition & Food Research. 10:e2200104. doi: 10.1002/mnfr.202200104.
  • Bocanegra A, Macho-González A, Garcimartín A, Benedí J, Sánchez-Muniz FJ (2021). Whole Alga, Algal Extracts, and Compounds as Ingredients of Functional Foods: Composition and Action Mechanism Relationships in the Prevention and Treatment of Type-2 Diabetes Mellitus. International Journal of Molecular Sciences. 22(8), 3816; doi: 10.3390/ijms22083816.
  • Macho-González A, Bastida S, Garcimartín A, López-Oliva ME, González P, Benedí J, González-Muñoz MJ, Sánchez-Muniz FJ (2021). Functional Meat Products as Oxidative Stress Modulators: A Review. Advances in Nutrition. 12(4):1514-1539; doi: 10.1093/advances/nmaa182.
  • Macho-González A, Garcimartín A, Redondo N, Cofrades S, Bastida S, Nova E, Benedí J, Sánchez-Muniz FJ, Marcos A, López-Oliva ME (2021). Carob fruit extract- enriched meat, as preventive and curative treatments, improves gut microbiota and colonic barrier integrity in a late-stage T2DM model. Food Research International. 141: 110124. doi: 10.1016/j.foodres.2021.110124.
  • Cofrades S, Garcimartín A, Gómez-Estaca J, Sánchez-Muniz FJ, Herranz B, Macho-González A, Benedí J, Álvarez MD (2020). The Effect of Emulsifying Protein and Addition of Condensed Tannins on n-3 PUFA Enriched Emulsions for Functional Foods. Foods. 9(11):E1589. doi: 10.3390/foods9111589.
  • Macho-González A, Garcimartín A, López-Oliva ME, Bastida S, Benedí J, Ros G, Nieto G, Sánchez-Muniz FJ. (2020) Can Meat and Meat-Products Induce Oxidative Stress? Antioxidants (Basel). 9(7): 638. doi: 10.3390/antiox9070638.
  • Macho-González A, López-Oliva ME, Merino JJ, García-Fernández R, Garcimartín A, Redondo-Castillejo R, Bastida S, Sánchez-Muniz FJ, Benedí J. (2020) Carob fruit extract-enriched meat improves pancreatic beta-cell dysfunction, hepatic insulin signaling and lipogenesis in late-stage type 2 diabetes mellitus model. Journal of Nutritional Biochemistry. 84:108461. doi: 10.1016/j.jnutbio.2020.108461.
  • Macho-González A, Garcimartín A, López-Oliva ME, Celada P, Bastida S, Benedí J, Sánchez-Muniz FJ. (2020) Carob-fruit-extract-enriched meat modulates lipoprotein metabolism and insulin signaling in diabetic rats induced by high-saturated-fat diet. Journal of Functional Foods. 64: 103600. doi.org/10.1016/j.jff.2019.103600.
  • Sánchez-Muniz FJ, Macho-González A, Garcimartín A, Santos-López JA, Benedí J, Bastida S, González-Muñoz MJ. (2019) The Nutritional Components of Beer and Its Relationship with Neurodegeneration and Alzheimer's Disease. Nutrients. 11(7). pii: E1558. doi: 10.3390/nu11071558.
  • Macho-González A, Garcimartín A, López-Oliva ME, Ruiz-Roso B, Martín de la Torre I, Bastida S, Benedí J, Sánchez-Muniz FJ. (2019) Can Carob-Fruit-Extract-Enriched Meat Improve the Lipoprotein Profile, VLDL-Oxidation, and LDL Receptor Levels Induced by an Atherogenic Diet in STZ-NAD-Diabetic Rats? Nutrients. 11(2). pii: E332. doi: 10.3390/nu11020332.
  • Macho-González A, Garcimartín A, Naes F, López-Oliva ME, Amores-Arrojo A, González-Muñoz MJ, Bastida S, Benedí J, Sánchez-Muniz FJ. (2018) Effects of Fiber Purified Extract of Carob Fruit on Fat Digestion and Postprandial Lipemia in Healthy Rats. Journal of Agricultural and Food Chemistry. 66(26):6734-6741. doi: 10.1021/acs.jafc.8b01476.
  • Macho-González A, Garcimartín A, López-Oliva ME, Bertocco G, Naes F, Bastida S, Sánchez-Muniz FJ, Benedí J. (2017). Fiber purified extracts of carob fruit decrease carbohydrate absorption. Food & Function, 8(6):2258-2265. doi: 10.1039/c7fo00166e.
  • Garcimartín A, López-Oliva ME, Macho-González A, Bastida S, Benedí J, Sánchez- Muniz FJ. (2017). Hypoglycaemic and hypotriglyceridaemic postprandial properties of organic silicon. Journal of Functional Foods, 29, 290-294. doi: 10.1016/j.jff.2016.12.040
  • Garcimartin A, López-Oliva ME, Santos-López JA, García-Fernández R, Macho- González A, Bastida S, Benedí, Sánchez-Muniz FJ. (2017). Silicon alleviates non- alcoholic steatohepatitis by reducing apoptosis in aged Wistar rats fed a high saturated fat, high cholesterol diet. Journal of Nutrition, 147(6):1104-1112. doi: 10.3945/jn.116.243204.

Graphical abstract: The preventive and therapeutic consumption of meat enriched with carob fruit extract, rich in phenolic compounds, improves colonic antioxidant status in late-stage T2DM rats


Proliferación celular colónica en un modelo animal de Diabetes Mellitus tipo 2

Proliferación celular colónica en un modelo animal de Diabetes Mellitus tipo 2


Figure 4. Can Carob-Fruit-Extract-Enriched Meat Improve the Lipoprotein Profile, VLDL-Oxidation, and LDL Receptor Levels Induced by an Atherogenic Diet in STZ-NAD-Diabetic Rats?