Complement physiopathology
Principal Investigator
Contact
egoicoec@ucm.es
Research
Elena Goicoechea de Jorge is a complement biologist whose main research interest is the study of the complement system and its association with pathology. Her research focuses in deciphering the molecular mechanisms by which dysregulation of the alternative pathway is associated with renal diseases including atypical haemolytic uremic syndrome, C3 glomerulopathy, IgA nephropathy and ANCA-associated vasculitis. In this context, understanding the biological role of the factor H-related protein family and how these proteins are involved in the pathogenesis of renal diseases is particularly important and represents the main research line in her lab. Her expertise includes genetics, molecular biology, biochemistry, cell biology and animal models of complement dysregulation.
After seven years of a fruitful postdoctoral period in the UK, she settled in Madrid as a principal investigator were she established her own group at the Complutense University in 2015.
Group members
Principal Investigator
Elena Goicoechea de Jorge
PhD students
Josué Gutiérrez Tenorio
Laura Lucientes Continente
Bárbara Márquez Tirado
Former members
Emilia Arjona Bolaños
Adara Llamas Gutiérrez