T cell physiopathology
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¿Qué hacemos en el laboratorio?
Topics
Research interests: αβ and γδ T cell and TCR physiopathology, the cellular dimension of complement defects, DNA repair pathways
Diagnostic procedures: T Cell Receptor immunodeficiencies, DNA repair defects
People, current position (pic)
- José R. Regueiro, Full Professor (2)
- María J. Recio, Associate Professor (1)
- Edgar Fernández-Malavé, Associate Professor (3)
- Paula P. Cárdenas, Assistant Professor (6)
- Anaïs Jiménez-Reinoso, postdoc (7)
- Ana V. Marin, UCM/Harvard PhD student (8)
- Alejandro C. Briones, PhD student (5)
- Rebeca Chaparro García, lab manager 2017 (9)-
- Sandra Medrano García, PhD student (4)
- Agustín Tortajada, Juan de la Cierva postdoc
Papers
- Blood 2018
- Semin Cell Dev Biol. 2018 Editorial
- Semin Cell Dev Biol. 2018
- J Allergy Clin Immunol 2018 C3 def
- Mol Immunol 2017 complement
- J Allergy Clin Immunol 2017 CD247 def T
- Nat Immunol 2016
- J Allergy Clin Immunol 2016 CD247 def NK
- LymphoSign J 2015
- Front Immunol 2015
- J Clin Invest 2014
- Cell Reports 2014
- J Allergy Clin Immunol 2014
- Inmunología 2013
- BMC Immunol 2013
- Oxford University Press 2013
- J Clin Invest 2011
TCR signal strength controls gd T cell differentiation. Nat Immunol 2016. "All models are wrong but some are useful" 1978, George Box, matemático británico.
Divulgación
TCRID diagnostic flowchart (Front Immunol 2015)
The gd TCR does not require the CD3 conformational change (Cell Reports 2014)
Libros sobre Inmunología
Meetings
People
(Primary immunodeficiency diseases 2013)
Divulgación científica
Cell type-specific role of Bcl-10 in NF-KB activation (J Clin Invest 2014)
Founder leaky CD3 delta mutations (J Clin Invest 2011)
