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Transfer and patents catalogs

 

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Transfer

Name of transfer activity University Area Focus area Name of the research group Researcher in charge Description of transfer activity (what it is, how it works)
Exhibions an Heritage consultancy KU Leuven Science and Engineering Cultural Heritage PADP (Perspectives on Architecture from the Distant Past) Prof. Dr. Merlijn Hurx: merlijn.hurx@kuleuven.be (1) Members of PADP have collaborated on, or even served as main curators of museum exhibitions in Belgium and abroad. Range: from supplying content, including products such as digital reconstructions, to involvement in design, dissemination, communication.(2) Members of PADP have fulfilled various consultancy roles in the professional world of heritage. Range: from strictly scientific advice to evaluation of projects as members of (state) commissions and members of heritage project teams in competition.
Consultancy Biogenomics European Marine Biology Resoruce Center Blue Cluster project Enzymares KU Leuven Science and Engineering One Health Biodiversity and Evolutionary Genomics Filip Volckaert: filip.volckaert@kuleuven.be The consultancy Biogenomics advises on and implements the application of genetics and genomics in non-model (wild) organisms from field to reporting. Examples are the sexing of birds, species identification, conservation genetics of birds and fish, and aquaculture genetics.The KU Leuven node of the European Marine Biology Resource Center (EMBRC.BE) advises on and implements the application of genomics in marine non-model (wild) organisms from field to reporting. Examples are the marine species identification, conservation genetics of fish, fisheries genetics and aquaculture genetics.The Flemish (Belgian) Blue Cluster project Enzymares explores the genomes of marine organisms with machine learning for unique enzymes with interesting industrial applications.
Design-oriented research KU Leuven Science and Engineering Cultural Heritage Research[x]Design (RxD) Prof. Andrew Vande Moere: andrew.vandemoere@kuleuven.be Exploratory design, implementation, deployment and evaluation of working prototypes in real-life contexts of innovative applications using emerging technologies.See for example: Citizen Dialog Kit http://citizendialogkit.org
Developed of biotization technology for commercial and ecological production of berry fruits Uniwersytet Jagielloński w Krakowie Science and Engineering One Health Plant-Microbial Interactions Team prof. Katarzyna Turnau: katarzyna.turnau@uj.edu.pl Developed the innovation which is the subject of patent: Biotization technology for commercial and ecological production of berry fruits. Realizing applicant projects together with the company, running contract research.
Developed two innovations which are the subject of patent application: Biotization technology for Brassicaceae and Plant growth-promoting microorganisms in metal-contaminated soil. Realizing applicant projects together with the company, running contract research. Uniwersytet Jagielloński w Krakowie Science and Engineering One Health Interactions of Plants with Microorganisms Dr hab. Piotr Rozpądek: piotr.rozpadek@uj.edu.pl Developed two innovations which are the subject of patent application: Biotization technology for Brassicaceae and Plant growth-promoting microorganisms in metal-contaminated soil. Realizing applicant projects together with the company, running contract research.
Developed two innovations, running contract research. Uniwersytet Jagielloński w Krakowie Science and Engineering One Health Aquatic Ecosystems Team Dr hab. Agnieszka Pajdak-Stós, assistant professor: agnieszka.pajdak-stos@uj.edu.pl Developed two innovations which are the subject of patent: Biological method of reducing excessive growth of filamentous bacteria in activated sludge in wastewater treatment plants and The method of intensive mass culture of Lecane rotifers. Running contract research for wastewater treatment plants
Development of inventions, innovations submitted for patent protection, running application projects Uniwersytet Jagielloński w Krakowie Science and Engineering One Health Department of Plant Cytology and Embryology Prof. Bartosz Płachno: bartosz.plachno@uj.edu.pl Developed the methods of culturing mesenchymal stem cells using secretionsfrom carnivorous plants, which increase cell adherence and proliferation, counteract theirtransformation into specialized cells, therefore, they longer maintain their pluripotency.
Development of medical chemistry programs UCM Science and engineering One Health Medicinal Chemistry Laboratory (MedChemLab) María Luz López Rodríguez: mluzlr@quim.ucm.es The Medicinal Chemistry Laboratory at the Universidad Complutense de Madrid (MedChemLab) develops research projects focused on the search of new therapeutic strategies for the identification of new effective treatments for high-incidence diseases. This objective is addressed through medicinal chemistry and chemical biology.The different medicinal chemistry projects encompass drug discovery programs, in which we develop new compounds with activity in different therapeutic targets and we study their potential for the treatment of specific pathologies, such as Parkinson's disease (allosteric modulators of dopamine D1 receptor), diabetes (allosteric modulators of glucagon-like peptide-1 receptor, GLP-1), spinal cord injury (lysophosphatidic acid receptor antagonists, especially the LPA1 and LPA2 subtypes), multiresistant bacterial infections (inhibitors of the bacterial protein FtsZ), and tuberculosis (antibody-drug conjugates). The different medicinal chemistry programs are carried out using methodologies developed in the MedChemLab:Design of new compounds using computational models: pharmacophore, virtual screening, docking, analysis of ADME parameters (clogP, solubility, stability, permeability, bioavailability).Synthesis of the proposed new compounds: design of the synthetic routes, set up of the reactions, preparation and purification of the desired products.In vitro screening of the new synthesized compounds: binding assays, cellular cytotoxicity, ELISA-type assays, calcium mobilization, protein expression levels, nuclear magnetic resonance experiments (STD, HSQC, ...), etc.ADME(T) properties and pharmacokinetic (PK) study of active compounds: solubility, chemical, serum and metabolic stability in liver microsomes (LM), albumin binding (HSA), cellular permeability (PAMPA), plasma and brain levels (B/P), cytochrome inhibition (CYP), cardiotoxicity (hERG).In vitro pharmacological characterization of selected compounds: functional activity (dose-response curves), selectivity, signaling pathways (calcium mobilization, protein phosphorylation), insulin secretion in pancreatic cells, phenotypic antibacterial study.
Electroanalytical biosensing platforms for the determination of methylations in nucleic acids at global and regional levels UCM Science and engineering One Health Electroanalysis and Electrochemical (Bio)Sensors  Susana Campuzano Ruiz: gebe@ucm.es The developed technologies allow the individual or simultaneous determination of the main methylated bases in DNA (5-methylcytosine, 5-mC and 5-hydroxymethylcytosine, 5-hmC) and RNA (N6-methyladenosine, m6A) both globally and regionally in a fast, reliable and simple way. The developed methodologies are based on the use of amperometric biosensors that employ micromagnetic carriers (MBs) functionalized with suitable bioreceptors and amperometric detection on disposable screen-printed electrodes.In these biodevices the amperometric signal obtained, which can be related to the amount of target methylated base, is based on the enzymatic and electrochemical reactions involved in the horseradish peroxidase (HRP)/hydroquinone (HQ)/H2O2 system that take place after the capture of the MBs on the surface of a disposable electrochemical transducer at an appropriate constant potential.
Flow/Mass Cytometry & Cell Sorting KU Leuven Science and Engineering One Health KU Leuven Flow and Mass Cytometry core facility Susan Schlenner: eu-info@kuleuven.be Flow/Mass cytometry allows for multi-parametric analyses of proteins (and other molecules) at a single cell level. Cells with phenotypes of interests can be purified during cell sorting.Available equipment among other (please consult our homepage as our equipment portfolio may change):> high-parameter spectral flow cytometers (SONY ID7000, Cytek Aurora)> high-parameter conventional flow cytometer (BD Symphony A5)> high-parameter mass cytometer (CyTOF Helios)> BSL2 cell sorters (SONY MA900, BD Influx)> single cell secretomics/phenomics (IsoPlexis IsoSpark)> flow cytometry training access and training on instrumentationPlease contact us at FACScorestaff@ls.kuleuven.be for service details.
Halide Sensors Alma Mater Studiorum Università di Bologna Science and Engineering Cultural Heritage Wearable/portable sensors Erika Scavetta: erika.scavetta2@unibo.it The invention refers to a new material that allows the creation of a two-terminal electrochemical sensor that maintains the transduction and amplification capabilities of a three-terminal transistor. The material can be designed to be sensitive to various anions such as chlorides, bromides, iodides, and sulphides present in the liquid under test. These innovative materials can be printed on various substrates such as glass, plastic and fabric, opening the doors to new types of sensors not achievable with traditional technologies, for example fully implemented inside a fabric or garment.
Health monitoring technology KU Leuven Science and Engineering One Health Measure, Model & Manage Bioresponses (M3-BIORES) Jean-Marie Aerts: jean-marie.aerts@kuleuven.be In the past our research group has, in collaboration with other research groups, developed technology that allows monitoring animal and human health. This has resulted in the foundation of four spin-off companies: BioRICS (founded in 2006, apps for mental load monitoring in humans, https://www.biorics.com/), SoundTalks (founded in 2011, technology for respiratory disease monitoring of pigs, https://www.soundtalks.com/), MyCellHub (founded in 2019, data management technology for cell production processes, https://www.mycellhub.com/) and CoMoveIT (founded in 2021, smart technology for steering electric wheelchairs for children suffering from cerebral palsy, https://comoveit.com/index.php/en/).
In vitro and in vivo research on gut health KU Leuven Science and Engineering One Health Nutrition and Animal Microbiota Ecosystems Nadia Everaert: eu-info@kuleuven.be In vitro digestion, fermentation or cell models on gut health. in vivo trials with sample analyses (pigs, chickens)
Micro and Nano Plastic Sensor Alma Mater Studiorum Università di Bologna Science and Engineering One Health Nanoparticles, Chemosensors and Nanotechnologies Luca Prodi: luca.prodi@unibo.it It’s a system to identify and quantify micro and nanoplastics, favoring both the detection and the recognition in water or in biological samples, in order to reduce environmental pollution. The invention aims to provide a solution to the problem of pollution from plastic in the environment using biocompatible materials that allow a quick and easy identification, and potentially quantification, of these fragments.
Mineral Oil Removal from Paper/Paperboard Alma Mater Studiorum Università di Bologna Science and Engineering One Health Analysis and monitoring of ecosystems Ilaria Braschi: ilaria.braschi@unibo.it Within the foodstuff packaging field, the currently available technologies enable limitation of organic contaminants migration from paper-based packaging to foodstuff through application of plastic, aluminum or activated carbon layers on/inside paper/paperboard foils. These technologies though require ad hoc paper production chains, whilst contaminants are not removed from packaging. The invention allows adsorbing and removing toxic contaminants (MOSH) and potential carcinogenic (MOAH) from paper/paperboard without the need to modify production line and without altering the cellulose neutral color. The patent claims the use of mesoporous silicas at high affinity for mineral oil. The silicas are thermally regenerable and reusable in numerous production cycles.
Solar Concentrator based on Silicon Nanostructure Alma Mater Studiorum Università di Bologna Science and Engineering Cultural Heritage Systems for artificial photosynthesis and photocatalysis Paola Ceroni: paola.ceroni@unibo.it The transparent material can be used in architectural elements such as windows and alike in order to obtain electricity from the sunlight, allowing greater sustainability of architectural structures such as museums, whose artworks must be constantly illuminated. Although systems based on low-cost high-performing solar cells are nowadays very reliable and extensively developed, further advances in solar cell technology are needed. Photovoltaics should become the largest source of energy and electricity in the world, in order to make a significant contribution to the renewable electricity generation. One of the solutions, being currently studied for the conversion of solar energy into electrical one, is precisely the use of luminescent solar concentrators