Grupos de investigación

Micronization by Supercritical AntiSolvent (SAS)

F. Zahran, P. Marzal, H.K. Ruiz, E. Pérez, L. Calvo, A.Cabañas,Micronization of ciprofloxacin by the Supercritical Antisolvent (SAS) Technique, The Journal of Supercritical Fluids, 2025, 215, 106413. https://doi.org/10.1016/j.supflu.2024.106413.

Ruiz, H.K.; Serrano, D.R.; Calvo, L.; Cabañas, A. Current Treatments for COVID-19: Application of Supercritical Fluids in the Manufacturing of Oral and Pulmonary Formulations. Pharmaceutics 2022, 14, 2380. https://doi.org/10.3390/pharmaceutics14112380

Cuadra I.A., Cabañas A., Cheda J.A.R., Türk M., Pando C. Cocrystallization of the anticancer drug 5-fluorouracil and coformers urea, thiourea or pyrazinamide using supercritical CO2 as an antisolvent (SAS) and as a solvent (CSS). REF. REVISTA: J. Supercrit Fluids 159, 104813 (2020) Impact Index: 3.481 (2018)Ranking:29/138          Engineering Chemical Q1 https://doi.org/10.1016/j.supflu.2020.104813

 Cuadra I., Zahran F., Martín D., Cabañas A., Pando, C., Preparation of 5-fluorouracil microparticles and 5-fluorouracil/poly(L-lactide) composites by a supercritical CO2 antisolvent process”, J. Supercrit. Fluids, 143, 64-71 (2019) Impact Index: 3.481 (2018) Ranking:  29/138  Engineering Chemical Q1 DOI:  10.1016/j.supflu.2018.07.027

 Cuadra I., Martinez-Casado, F.J., Cheda J.A.R., Redondo M.I., Cabañas A; Pando, C., Production and characterization of a new Copper(II) propanoate-Isonicotinamide adduct obtained via Slow Evaporation and using Supercritical CO2 as an Antisolvent, Crystal Growth & Design 19, 620–629 (2019) Impact Index: 4.153    (2018)  Ranking: 66/293  Material Science, Multidisciplinary Q1  DOI: 10.1021/acs.cgd.8b01034

Cuadra I., Zahran F., Martín D., Cabañas A., Pando, C., Preparation of 5-fluorouracil microparticles and 5-fluorouracil/poly(L-lactide) composites by a supercritical CO2 antisolvent process, J. Supercrit. Fluids, 143, 64-71 (2019) Impact Index: 3.481 (2018)    Ranking: 29/138  Engineering Chemical Q1 DOI:  10.1016/j.supflu.2018.07.027

I. Cuadra, A. Cabañas J.A.R. Cheda, F.J Martínez-Casado and  C. Pando, Pharmaceutical co-crystals of the anti-inflammatory drug diflunisal and nicotinamide obtained using supercritical CO2 as an antisolvent, J. CO2 Utilization 13, 29-37 (2016)  Impact Index: 4.292 (2016) Ranking: 15/135 Engineering Chemical Q1 and Chemistry, multidisciplinary 33/166 Q1   DOI: 10.1016/j.jcou.2015.11.006

C. Pando, A. Cabañas and I. Cuadra,Preparation of pharmaceutical co-crystals through sustainable processes using supercritical carbon dioxide: a review RSC Adv., 6, 71134-71150(2016)  Impact Index:   3.108  Ranking:  59/166  Chemistry, Multidisciplinary Q2    DOI: 10.1039/c6ra10917a

 F. Zahran, A. Cabañas, J.A.R. Cheda, J.A. R. Renuncio and C. Pando, Dissolution rate enhancement of the anti-inflammatory drug diflunisal by coprecipitation with a biocompatible polymer using carbon dioxide as a supercritical fluid antisolvent, J. Supercrit. Fluids, 88, 56–65 (2014)  Impact Index: 2.371    Ranking: 37/135 Engineering Chemical Q2 DOI: /10.1016/j.supflu.2014.01.015