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Research Teams and Lines

2004-2006

VIP and tolerance induction in autoimmunity

Rosignoli F, Torroba M, Juarranz Y, García-Gómez M, Martínez C, Gomariz RP, Pérez-Leirós C, Leceta J.

Ann N Y Acad Sci. 2006 Jul;1070:525-30.

PAC1 receptor: emerging target for septic shock therapy

Martínez C, Arranz A, Juarranz Y, Abad C, García-Gómez M, Rosignoli F, Leceta J, Gomariz RP.

Ann N Y Acad Sci. 2006 Jul;1070:405-10.

VIP decreases TLR4 expression induced by LPS and TNF-alpha treatment in human synovial fibroblasts

Juarranz Y, Gutiérrez-Cañas I, Arranz A, Martínez C, Abad C, Leceta J, Pablos JL, Gomariz RP.

Ann N Y Acad Sci. 2006 Jul;1070:359-64.

Effect of VIP on TLR2 and TLR4 expression in lymph node immune cells during TNBS-induced colitis

Arranz A, Abad C, Juarranz Y, Torroba M, Rosignoli F, Leceta J, Gomariz RP, Martínez C.

Ann N Y Acad Sci. 2006 Jul;1070:129-34.

VIP-PACAP system in immunity: new insights for multitarget therapy

Gomariz RP, Juarranz Y, Abad C, Arranz A, Leceta J, Martínez C.

Ann N Y Acad Sci. 2006 Jul;1070:51-74.

Neuropeptide mimetics and antagonists in the treatment of inflammatory disease: focus on VIP and PACAP

Abad C, Gomariz RP, Waschek JA.

Curr Top Med Chem. 2006;6(2):151-63.

VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts

Gutiérrez-Cañas I, Juarranz Y, Santiago B, Arranz A, Martínez C, Galindo M, Payá M, Gomariz RP, Pablos JL.

Rheumatology (Oxford). 2006 May;45(5):527-32. PDF

CXCL12 is displayed by rheumatoid endothelial cells through its basic amino-terminal motif on heparan sulfate proteoglycans

Santiago B, Baleux F, Palao G, Gutiérrez-Cañas I, Ramírez JC, Arenzana-Seisdedos F, Pablos JL.

Arthritis Res Ther. 2006;8(2):R43. PDF

Defective signalling in salivary glands precedes the autoimmune response in the non-obese diabetic mouse model of sialadenitis

Rosignoli F, Roca V, Meiss R, Leceta J, Gomariz RP, Pérez Leirós C.

Clin Exp Immunol. 2005 Dec;142(3):411-8. PDF

Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis

Juarranz Y, Abad C, Martínez C, Arranz A, Gutiérrez-Cañas I, Rosignoli F, Gomariz RP, Leceta J.

Arthritis Res Ther. 2005;7(5):R1034-45. PDF

cDNA array analysis of cytokines, chemokines, and receptors involved in the development of TNBS-induced colitis: homeostatic role of VIP

Abad C, Juarranz Y, Martínez C, Arranz A, Rosignoli F, García-Gómez M, Leceta J, Gomariz RP.

Inflamm Bowel Dis. 2005 Jul;11(7):674-84.

Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP

Gomariz RP, Arranz A, Abad C, Torroba M, Martínez C, Rosignoli F, Garcia-Gómez M, Leceta J, Juarranz Y.

J Leukoc Biol. 2005 Aug;78(2):491-502. PDF

Analysis of the role of the PAC1 receptor in neutrophil recruitment, acute-phase response, and nitric oxide production in septic shock

Martínez C, Juarranz Y, Abad C, Arranz A, Miguel BG, Rosignoli F, Leceta J, Gomariz RP.

J Leukoc Biol. 2005 May;77(5):729-38. PDF

Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis

Santiago B, Gutiérrez-Cañas I, Dotor J, Palao G, Lasarte JJ, Ruiz J, Prieto J, Borrás-Cuesta F, Pablos JL.

J Invest Dermatol. 2005 Sep;125(3):450-5. PDF

Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II

Galindo M, Santiago B, Palao G, Gutiérrez-Cañas I, Ramirez JC, Pablos JL.

Peptides. 2005 Sep;26(9):1647-53.

Vasoactive intestinal peptide induces neuroendocrine differentiation in the LNCaP prostate cancer cell line through PKA, ERK, and PI3K

Gutiérrez-Cañas I, Juarranz MG, Collado B, Rodríguez-Henche N, Chiloeches A, Prieto JC, Carmena MJ.

Prostate. 2005 Apr 1;63(1):44-55.

Induction of neuropeptide gene expression and blockade of retrograde transport in facial motor neurons following local peripheral nerve inflammation in severe combined immunodeficiency and BALB/C mice

Armstrong BD, Hu Z, Abad C, Yamamoto M, Rodríguez WI, Cheng J, Lee M, Chhith S, Gomariz RP, Waschek JA.

Neuroscience. 2004;129(1):93-9.

Vasoactive intestinal peptide modulates proinflammatory mediator synthesis in osteoarthritic and rheumatoid synovial cells

Juarranz MG, Santiago B, Torroba M, Gutiérrez-Cañas I, Palao G, Galindo M, Abad C, Martínez C, Leceta J, Pablos JL, Gomariz RP.

Rheumatology (Oxford). 2004 Apr;43(4):416-22. PDF

Vasoactive intestinal peptide increases vascular endothelial growth factor expression and neuroendocrine differentiation in human prostate cancer LNCaP cells

Collado B, Gutiérrez-Cañas I, Rodríguez-Henche N, Prieto JC, Carmena MJ.

Regul Pept. 2004 Jun 15;119(1-2):69-75.