JEFE GRUPO (CÁNCER DE MAMA) : CRISTINA SÁNCHEZ

 

Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer

Tundidor, I., Seijo-Vila, M., Blasco-Benito, S., Rubert-Hernández, M., Adámez, S., Andradas, C., Manzano, S., Álvarez-López, I., Sarasqueta, C., Villa-Morales, M., González-Lois, C., Ramírez-Medina, E., Almoguera, B., Sánchez-López, A.J., Bindila, L., Hamann, S., Arnold, N., Röcken, C., Heras-Murillo, I., Sancho, D., Moreno-Bueno, G., Caffarel, M.M., Guzmán, M., Sánchez, C., Pérez-Gómez, E. 

Nature Communications 2023

 

Therapeutic targeting of HER2-CB₂R heteromers in HER2-positive breast cancer.

Blasco-Benito, S., Moreno, E., Seijo-Vila, M., Tundidor, I., Andradas, C., Caffarel, MM., Caro-Villalobos, M., Urigüen, L., Diez-Alarcia, R., Moreno-Bueno, G., Hernández, L., Manso, L., Homar-Ruano, P., McCormick, P.J., Bibic, L., Bernadó-Morales, C., Arribas, J., Canals, M., Casadó, V., Canela, E.I., Guzmán, M., Pérez-Gómez, E., Sánchez, C. 

Proceedings of the National Academy of Sciences of the United States of America 2019

 

Appraising the «entourage effect»: Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer

Blasco-Benito, S., Seijo-Vila, M., Caro-Villalobos, M., Tundidor, I., Andradas, C., García-Taboada, E., Wade, J., Smith, S., Guzmán, M., Pérez-Gómez, E., Gordon, M., Sánchez, C. 

Biochemical Pharmacology 2018

 

In situ localization of tumor cells associated with the epithelial-mesenchymal transition marker Snail and the prognostic impact of lymphocytes in the tumor microenvironment in invasive ductal breast cancer.

Alkatout, I., Hübner, F., Wenners, A., Hedderich, J., Wiedermann, M., Sánchez, C., Röcken, C., Mathiak, M., Maass, N., Klapper, W. 

Experimental and Molecular Pathology 2017

 

Loss of cannabinoid CB1 receptors induces cortical migration malformations and increases seizure susceptibility. 

Díaz-Alonso, J., de Salas-Quiroga, A., Paraíso-Luna, J., García-Rincón, D., Garcez, P., Parsons, M., Andradas, C. Sánchez, C., Guillemot, F., Guzmán, M., Galve-Roperh, I. 

Cerebral Cortex 2016

 

Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer

Andradas, C., Blasco-Benito, S., Castillo-LLuva, S., Dillenburg-Pilla, P., Diez-Alarcia, R., Juanes-García, A., García-Taboada, E., Hernando-Llorente, R., Soriano, J., Hammann, S., Wenners, A., Alkatout, I., Klapper, W., Rocken, C., Bauer, M., Arnold, N., Quintanilla, M., Megías, D., Vicente-Manzanares, M., Urigüen, L., Gutkind, J.S., Guzmán, M., Pérez-Gómez, E.,  Sánchez, C. 

Oncotarget 2016

 

Anticancer mechanisms of cannabinoids

Velasco, G., Sánchez, C., Guzmán, M. 

Current Oncology 2016

 

New inhibitors of angiogenesis with antitumor activity in vivo

Marín-Ramos, N., Alonso, D.,  Ortega-Gutierrez, S., Ortega-Nogales, F., Balabasquer, M., Vazquez-Villa, H., Andradas, C.  Blasco-Benito, S., Pérez-Gómez, E., Canales, A., Jiménez-Barbero, J., Marquina, A., Moscoso del Prado, J., Sánchez, C., Martín-Fontecha, M., López-Rodrí­guez, M. 

Journal of Medicinal Chemistry 2015

 

Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin alpha-sarcin in nude mice bearing human colorectal cancer xenografts.

Tomé-Amat, J., Olombrada, M., Ruiz-de-la-Herrán, J., Pérez-Gómez, E., Andradas, C., Sánchez, C., Martínez, L., Martínez-del-Pozo, Á., Gavilanes, J.G.,  Lacadena, J. 

SpringerPlus 2015

 

Selective, non-toxic CB2 cannabinoid o-quinone with in vivo activity against triple negative breast cancer. 

Morales, P., Blasco-Benito, S., Andradas, C., Gómez-Cañas, M., Flores, J.M., Goya, P., Fernández-Ruiz, J.J., Sánchez, C., Jagerovic N.

Journal of Medicinal Chemistry 2015

 

Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer

Pérez-Gómez, E., Andradas, C., Blasco-Benito, S., Caffarel, M.M., García-Taboada, E., Villa-Morales, M., Moreno, E., Hamann, S., Martín-Villar, E., Flores, J.M., Wenners, A., Alkatout, I., Klapper, W., Röcken, C., Bronsert, P., Stickeler, E., Staebler, A., Bauer, M., Arnold, N., Soriano, J., Pérez-Martínez, M., Megías, D., Moreno-Bueno, G., Ortega-Gutiérrez, S., Artola, M., Vázquez-Villa, H., Quintanilla, M., Fernández-Piqueras, J., Canela, E.I., McCormick, P.J, Guzmán M., Sánchez, C. 

Journal of the National Cancer Institute 2015

 

TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling

Salazar, M., Lorente, M., García-Taboada, E., Pérez-Gómez, E., Dávila, D., Zúñiga-García, P., Flores, J.M., Rodríguez, A., Hegedus, Z., Mosén-Ansorena, D., Aransay, A., Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J., Dusetti, N., Guzmán, M., Francis, S., Carracedo, A., Kiss-Toth, E., Velasco, G. 

Molecular & Cellular Oncology 2015

 

 Endocannabinoids and Cancer

Velasco, G., Sánchez, C., Guzmán, M. 

Handbook of Experimental Pharmacology 2015

 

Some potential therapeutic targets for phytocannabinoids: cancer

Velasco, G., Sánchez, C., Guzmán, M., 

Handbook of Cannabis (ISBN: 978-0-19-966268-5) 2014

 

Loss of Tribbles pseudokinase-3 promotes AKT-driven tumorigenesis via FOXO inactivation

Salazar, M., Lorente, M.,  García-Taboada, E., Pérez-Gómez, E., Dávila, D., Zúñiga-García, P., Flores, J.M., A. Rodríguez, Hegedus, Z., Mosén-Ansorena, D., Aransay, A.  Hernández-Tiedra, S., López-Valero, I., Quintanilla, M., Sánchez, C., Iovanna, J., Dusetti, N., Guzmán, M., Francis, S., Carracedo, A., Kiss-Toth, E., Velasco, G. 

Cell Death & Differentiation 2015

 

Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling

Moreno, E., Andradas, C., Medrano, M., Caffarel, M.M., Pérez-Gómez, E., Blasco-Benito, S., Gómez-Cañas, M., Pazos, M.R., Irving, A.J., Lluís, C., Canela, E.I., Fernández-Ruiz, J.J., Guzmán, M., McCormick, P.J., Sánchez, C. 

Journal of Biological Chemistry 2014

 

The orphan receptor GPR55 drives skin carcinogenesis and is upregulated in human squamous cell carcinomas

Pérez-Gómez, E., Andradas, C., Flores, J.M., Quintanilla, M., Paramio, J.M., Guzmán, M., Sánchez, C. 

Oncogene 2013

 

The role of GPR55 in cancer. Endocannabinoids: actions at non-CB1/CB2 cannabinoid receptors

Andradas, C., Caffarel, M.M., Pérez-Gómez, E., Guzmán, M., Sánchez, C., (2013) The role of GPR55 in cancer. 

(ISBN: 978-1-4614-4668-2).

 

Cannabinoids: a new hope for breast cancer therapy?

Caffarel, M.M., Andradas, C., Pérez-Gómez, E., Guzmán, M., Sánchez, C. 

Cancer Treatment Reviews 2012

 

Towards the use of cannabinoids as antitumour agents

Velasco, G., Sánchez, C., Guzmán, M.

Nature Reviews Cancer 2012