Recent Publications
The F-Actin Binding Protein Cortactin Regulates the Dynamics of the Exocytotic Fusion Pore through its SH3 Domain.
González-Jamett AM, Guerra MJ, Olivares MJ, Haro-Acuña V, Baéz-Matus X, Vásquez-Navarrete J, Momboisse F, Martinez-Quiles N, Cárdenas AM.
Front Cell Neurosci. 2017 May 4;11:130. doi: 10.3389/fncel.2017.00130. eCollection 2017.
PMID: 28522963
HLA-DMB in Amerindians: Specific linkage of DMB*01:03:01/DRB1 alleles.
Arnaiz-Villena A, Palacio-Grüber J, Muñiz E, Rey D, Recio MJ, Campos C, Martinez-Quiles N, Martin-Villa JM, Martinez-Laso J.
Hum Immunol. 2016 May;77(5):389-94. doi: 10.1016/j.humimm.2016.02.011. Epub 2016 Mar 2.
PMID: 26944519
Characterisation and functional implications of the two new HLA-G alleles found in Amerindian and Caribbean populations.
Arnaiz-Villena A, Enriquez-de-Salamanca M, Palacio-Grüber J, Campos C, Camacho A, Martin-Villa JM, Martinez-Quiles N, Gomez-Casado E, Muñiz E.
Hum Immunol. 2016 Sep;77(9):812-6. doi: 10.1016/j.humimm.2016.01.006. Epub 2016 Jan 18.
PMID: 26796363
Contribution of Crk adaptor proteins to host cell and bacteria interactions.
Martinez-Quiles N, Feuerbacher LA, Benito-León M, Hardwidge PR.
Biomed Res Int. 2014;2014:372901. doi: 10.1155/2014/372901. Epub 2014 Nov 25. Review.
PMID: 25506591
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector.
Nieto-Pelegrin E, Kenny B, Martinez-Quiles N.
Cell Adh Migr. 2014;8(4):404-17. doi: 10.4161/19336918.2014.969993.
PMID: 25482634
Src Kinases Regulate De Novo Actin Polymerization during Exocytosis in Neuroendocrine Chromaffin Cells.
Olivares MJ, González-Jamett AM, Guerra MJ, Baez-Matus X, Haro-Acuña V, Martínez-Quiles N, Cárdenas AM.
PLoS One. 2014 Jun 5;9(6):e99001. doi: 10.1371/journal.pone.0099001. eCollection 2014. PubMed PMID: 24901433.
http://www.ncbi.nlm.nih.gov/pubmed/24901433
Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector. Plos Pathogens
Nieto-Pelegrin E, Meiler E, Martín-Villa JM, Benito-León M, Martinez-Quiles N.
PLoS Pathog. 2014 Mar 27;10(3):e1004022. doi: 10.1371/journal.ppat.1004022. eCollection 2014 Mar.
PMID: 24675776
http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004022
Martínez-Quiles N
Emerging roles of hematopoietic lineage cell-specific protein 1 (HS1) in the immune system
OA Immunol: OA Immunology 2013 Apr 01;1(1):2. REVIEW
https://www.oapublishinglondon.com/article/432
PMID: 22761768 (http://www.ncbi.nlm.nih.gov/pubmed/22761768)
Eliana Rosales1, Milton Aguilera1, Romina Salinas1, Sergio Carminati1, Narcisa Martinez-Quiles2 and Walter Berón1.
1 Instituto de Histología y Embriología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo - CONICET, Mendoza, 5500, Argentina, 2 Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid, España.
Cortactin is involved in the entry of Coxiella burnetii into nonphagocytic cells
PLoS One. 2012;7(6):e39348.
22 jun 2012
PMID: 22479425 (http://www.ncbi.nlm.nih.gov/pubmed/22479425)
Eugenia Meiler, Elvira Nieto-Pelegrín and Narcisa Martinez-Quiles.
Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading
PloS One, Volume 7(Issue3)e33662
30 March 2012
http://dx.plos.org/10.1371/journal.pone.0033662
Highlighted in “Global Medical Discovery”
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PMID: 21669400 (http://www.ncbi.nlm.nih.gov/pubmed/21669400)
Nicole Tegtmeyer1, Ruth Wittelsberger1, Roland Hartig2, Silja Wessler3, Narcisa Martinez-Quiles4, Steffen Backert1.
1 Dept. of Microbiology and 2 Dept. of Immunology, Otto von Guericke University,
Leipziger Str. 44, D-39120 Magdeburg, Germany
3 Dept. Molecular Biology, Section Microbiology, University Salzburg, Billrothstraße 11 5020 Salzburg, Austria.
4 Microbiología II. Facultad de Farmacia, Universidad Complutense de Madrid, Avda de la Complutense s/n. 28040 Madrid, Spain
Serine Phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori.
Cell Host and Microbe 2011 Jun 16;9(6):520-31
16 June 2011
Highlighted in Madri I+D org (Notiweb) (3-10-2011), Noticias OTRI-Complutense, Diario ABC (abc salud) etc.
PMID: 19438518 (http://www.ncbi.nlm.nih.gov/pubmed/19438518)
Sabine Brandt1, Brendan Kenny2, Manfred Rohde3, Narcisa Martinez-Quiles4 and Steffen Backert1.
1Department of Medical Microbiology, Otto von Guericke University, Leipziger Str. 44, D-39120 Magdeburg, Germany
2Institute for Cell and Molecular Biosciences, Medical School, University of Newcastle, Newcastle NE2 4HH, UK
3German Research Centre for Biotechnology (GBF), Mascheroder Weg 1, D-38124 Braunschweig, Germany
4Microbiología II. Facultad de Farmacia. Universidad Complutense de Madrid, Avda de la Complutense s/n. 28040 Madrid, Spain
Dual infection of mammalian cells provides novel insights into injected bacterial effector protein function.
Cellular Microbiology (2009) 11 (8): 1254-1271.
PMID: 19419567 (http://www.ncbi.nlm.nih.gov/pubmed/19419567
Nieto-Pelegrín E and Martínez Quiles N.
Distinct phosphorylation requirements regulate cortactin activation by Tir EPEC and its binding to N-WASP
Cell Communication and Signaling 2009, 7: 11 (8): 1254-71