PRINCIPAL INVESTIGATORS:  María Teresa Villalba Díaz 

 

GROUP MEMBERS

• Eva Batanero Cremades
• Javier Turnay Abad
• Nieves Olmo López
• Carlos Pastor
• Cristina Bueno
• Selene Martínez
• Jorge Parrón
• Francisco Martínez Carmona
• Rubén García Gordo
• Estela Martínez
• Iñigo Arauco

 

GENERAL AIMS OF THE GROUP

 

Identification and structural and immunologic characterization of molecules responsible for allergic responses. Recombinant production of allergens.

Role of bronchial and intestinal epithelial barrier in the development of allergy.

Study of the molecular mechanisms of differentiation and death (apoptosis) in human colon adenocarcinoma cells. Role of annexins.

 

LINES OF THE RESEARCH GROUP AND RESPONSIBLE RESEARCHER

 

• Structural and immunological study of pollen and food allergens Production of recombinant allergens and hypoallergenic derivatives. (María Teresa Villalba Díaz y Carlos Pastor Vargas)
• Role of bronchial epithelium in allergic response. Influence of environmental factors. (Eva Batanero Cremades)
• Influence of the metabolites released by the microbiota on the response of the intestinal epithelium to food allergens. (Javier Turnay y Eva Batanero)
• Effect of short chain fatty acids (SCFA) such as butyrate on the molecular mechanisms involved in resistance to apoptosis and increase of tumorigenicity. Role of annexins. (Javier Turnay y Nieves Olmo)